PCNA anticorps
Aperçu rapide pour PCNA anticorps (ABIN7467900)
Antigène
Voir toutes PCNA AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Réactivité croisée
- Humain, Souris, Rat
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Purification
- Protein G purified
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Immunogène
- Recombinant PCNA interdomain connector loop protein
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Isotype
- IgG1
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Indications d'application
- WB: 1:500-1:1000. ICC/IF: 1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS, No Preservative
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Agent conservateur
- Without preservative
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- PCNA (Proliferating Cell Nuclear Antigen (PCNA))
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Autre désignation
- proliferating cell nuclear antigen
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Sujet
- Proliferating cell nuclear antigen , ATLD2,The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome. [provided by RefSeq, Jul 2008]
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Poids moléculaire
- 29 kDa
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ID gène
- 5111
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UniProt
- P12004
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Pathways
- Telomere Maintenance, Réparation de l'ADN, Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Autophagy
Antigène
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